Some antidepressants may work better than others long term - new study

A new study published in The Lancet Psychiatry suggests that certain antidepressants, such as Lexapro and Cymbalta, may be more effective for long-term symptom management than others. The research also highlights the prevalence of long-term antidepressant use in Australia.
Why it matters
Understanding the comparative efficacy of psychiatric medications is vital for public health and clinical treatment guidelines.
Tara Winstead/Pexels A new review has found some antidepressants may be more effective than others at helping people reduce the severity of their symptoms of depression over the long term.
The research, published in The Lancet Psychiatry, found people taking escitalopram (commonly sold as Lexapro), duloxetine (Cymbalta) and agomelatine (Valdoxan) were more likely to report improved symptoms over the long term than those taking fluoxetine (Prozac). For those taking Lexapro and Cymbalta, they were also more likely to stay on their medications.
But does that mean these are the best antidepressants?
Around one in seven Australians will experience depression during their lifetime.
Treatment can involve psychological therapies, social support and lifestyle changes, such as doing more exercise. For some people, these approaches may be enough to support recovery. For others, adding an antidepressant can be an important part of treatment.
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