Some Antidepressants May Work Better Long Term, Study Finds
A new study published in The Lancet Psychiatry suggests that certain antidepressants, such as escitalopram and duloxetine, may be more effective for long-term symptom management than others. The research highlights the importance of gradual discontinuation and medical supervision when stopping treatment.
Why it matters
With millions of prescriptions issued annually, identifying the most effective long-term treatments for depression is critical for improving patient outcomes and managing medication dependency.
A new review has found some antidepressants may be more effective than others at helping people reduce the severity of their symptoms of depression over the long term.
Lecturer in Pharmacy and Pharmacology, Adelaide University
Senior Lecturer in Pharmacy Practice, Adelaide University
The research, published in The Lancet Psychiatry, found people taking escitalopram (commonly sold as Lexapro), duloxetine (Cymbalta) and agomelatine (Valdoxan) were more likely to report improved symptoms over the long term than those taking fluoxetine (Prozac). For those taking Lexapro and Cymbalta, they were also more likely to stay on their medications.
But does that mean these are the best antidepressants?
Around one in seven Australians will experience depression during their lifetime.
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