Zepbound and Mounjaro may turn on the body’s calorie-burning brown fat

Tirzepatide has become an important treatment for obesity and related conditions such as diabetes, but scientists are still working to understand exactly how it affects the body. A study in mice now suggests that the drug may improve metabolism directly by activating brown adipose tissue, a form of fat that specializes in using energy.

According to the researchers, the findings provide new clues about how tirzepatide works and could help guide the development of broader treatments for obesity and other metabolic disorders.

The research was led by Marion Peyrou, Ram n y Cajal researcher at the Faculty of Biology and the Institute of Biomedicine of the University of Barcelona (IBUB), the Sant Joan de D u Research Institute (IRSJD) and the CIBER in Physiopathology of Obesity and Nutrition (CIBEROBN).

Tirzepatide Targets Two Hormone Receptors