Yale scientists may have found how Parkinson's disease spreads through the brain
Yale researchers have identified two proteins, mGluR4 and NPDC1, that facilitate the spread of misfolded alpha-synuclein proteins between neurons in Parkinson's disease. This discovery provides a potential target for new therapies aimed at slowing or halting the progression of the neurological disorder.
Why it matters
Understanding the molecular mechanism of protein transmission could lead to breakthrough treatments for millions of Parkinson's patients worldwide.
Parkinson's disease may spread through the brain with the help of two proteins found on the surface of motor neurons, according to new research from Yale School of Medicine (YSM). The discovery could open the door to treatments designed to slow or even stop the disease instead of only managing its symptoms.
The article reports on scientific research findings without political or social commentary.
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