World's largest psilocybin brain-imaging study maps how context reshapes psychedelic effects

A Monash University study using brain imaging has revealed how psilocybin reorganizes brain networks based on a person's environment and focus. The research suggests that context plays a critical role in the therapeutic potential of psychedelic experiences.
Why it matters
Understanding how external factors influence brain activity under psychedelics could lead to more effective, personalized mental health treatments.
edited by Swati Mestri , reviewed by Andrew Zinin
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Add as preferred source Credit: Pixabay/CC0 Public Domain A landmark five-year study by Monash University has found psychedelics reorganize brain patterns, giving clinicians powerful new insights into their therapeutic potential.
Published in the journal Nature , the research is the world's largest single-site brain-imaging study of the acute effects of psilocybin, the psychedelic compound found in magic mushrooms.
Researchers used brain imaging to understand what happened in the brains of 62 healthy adults receiving psilocybin while resting, meditating, listening to music and watching a movie.
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