What's the neuroscience behind a 'runner's high'?
Neuroscientists are re-evaluating the biological causes of the 'runner's high,' moving away from the traditional focus on endorphins. Current research suggests the phenomenon results from a complex interaction of multiple brain systems.
Why it matters
Understanding the neurological basis of exercise-induced euphoria can improve mental health treatments and exercise science protocols.
Exercising until you reach a temporary state of euphoria, calm, or clarity delivers much more than pleasure.
Laura Elin Pigott for 9 August 2026 7 min read Caption: When someone is running, activity within the regions of their brain associated with self-reflection, worry and thinking appears to decrease. Photo credit: Venti Views / Unsplash While most runners are chasing after a new goal or a personal best, some are chasing after something slightly more elusive: a runner’s high. Some describe it as euphoria. Others as calm, clarity or even a sense of being completely absorbed in the moment. Many people experience some version of it after a long run or a spin class.
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