Video Eye Drop Test Identifies Diabetic Peripheral Neuropathy
A pilot study has demonstrated that a video-based eye drop test can effectively detect diabetic peripheral neuropathy by measuring corneal chemical sensitivity. The test outperformed traditional mechanical methods in identifying nerve damage in patients with type 2 diabetes.
Why it matters
Offers a non-invasive, objective diagnostic tool that could improve early detection and monitoring of diabetic nerve damage.
An objective, video-based corneal chemical sensitivity test can effectively, noninvasively detect diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes, according to a pilot study published in Cornea.
The study, conducted by researchers at the Department of Veterans Affairs Iowa City Health Care System, evaluated a novel functional assay that measures reflex blinking and squinting induced by hyperosmolar eye drops.
The investigators evaluated 14 patients with type 2 diabetes and verified DPN alongside 8 nondiabetic controls. They quantified the percentage of time eyelids remained closed for 50 seconds following administration of an isotonic saline solution vs a hypertonic 5% NaCl solution.
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