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Nature·5 min read·hard

VDAC1 regulates disulfidptosis susceptibility and associates with the immune microenvironment via multi-omics analysis in lung adenocarcinoma

C
Chen, Chen
VDAC1 regulates disulfidptosis susceptibility and associates with the immune microenvironment via multi-omics analysis in lung adenocarcinoma
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A multi-omics analysis of lung adenocarcinoma (LUAD) identifies VDAC1 as a key biomarker associated with poor prognosis and therapy resistance. The study links VDAC1 to disulfidptosis and an immunosuppressive tumor microenvironment.

Why it matters

Identifying VDAC1 as a therapeutic target could lead to more effective treatments for lung cancer patients who currently face high mortality rates.

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Scientific Reports ( 2026 ) Cite this article

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply.

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