Twisted laser light distinguishes mirror-image molecules by their fragment counts

Researchers have developed a method using 'twisted' laser light to distinguish between mirror-image chiral molecules. This technique allows scientists to identify specific molecular handedness, which is crucial for pharmaceutical and biological applications.
Why it matters
Improving the ability to distinguish between enantiomers can lead to safer and more effective drug development.
by Tata Institute of Fundamental Research
edited by Lisa Lock , reviewed by Robert Egan
This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility:
Add as preferred source Schematic illustration of twisted-light interaction with chiral camphor. Credit: Ram Gopal, TIFR Hyderabad Many molecules exist in two mirror-image forms—like left and right hands—that look identical but can behave very differently, especially in biological systems and pharmaceuticals. Distinguishing between these enantiomers (also called chiral molecules) is a longstanding challenge in science and technology. A useful analogy is that of a screw and a nut: A right-handed screw fits only into a right-handed thread, while a left-handed one will not engage properly.
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