Three studies map how superbugs evade antibiotics and spread to vulnerable patients

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Add as preferred source Volcano plot of overrepresented genes in H10544. Credit: Antimicrobial Agents and Chemotherapy (2026). DOI: 10.1128/aac.00506-26 To defeat multidrug-resistant superbugs, bacterial defenses must be confronted wherever they may emerge, from basic genetic mutations in a laboratory to complex real-world transmission in hospital rooms. A new trio of studies published in Antimicrobial Agents and Chemotherapy and researched by the laboratory of Barry N. Kreiswirth, Ph.D., at the Hackensack Meridian Center for Discovery and Innovation (CDI) demonstrates how an integrated approach might yet expose and overcome these diverse survival mechanisms.

The Kreiswirth Lab continues to focus on different aspects of antimicrobial resistance (AMR), and Kreiswirth himself has driven or collaborated on these AAC studies.