This pet gecko could help scientists unlock the secrets of cancer
Scientists have identified a specific leopard gecko morph, known as 'lemon frost,' that is highly susceptible to developing cancer. Researchers believe studying the genetic mutations in these reptiles could provide a new model for understanding tumor formation and resistance in humans.
Why it matters
Using naturally occurring cancer models in animals can accelerate the discovery of new prevention and treatment strategies for human oncology.
A colorful pet gecko that is unusually prone to developing cancer could become an important new tool for researchers studying how tumors form and spread. Scientists say the animal's naturally occurring cancers may offer valuable insights into why some species are highly vulnerable to the disease while others are remarkably resistant.
The research, led by the University of Nottingham and published in BMC Biology , identified genetic changes linked to tumors in a special variety of leopard gecko. Many of those changes involve the same genes and biological pathways associated with human cancers, raising the possibility that this reptile could help advance cancer research.
Among reptiles, cancer risk varies widely. Turtles and tortoises rarely develop the disease, but a white and yellow leopard gecko known in the pet trade as the "lemon frost" morph develops aggressive tumors in about 80% of individuals.
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