The Wnt co-receptor Arrow-LRP5/6 is required for planar cell polarity establishment in Drosophila
Researchers have discovered that the Wnt co-receptor Arrow-LRP5/6 is essential for establishing planar cell polarity in Drosophila. This finding challenges previous models that suggested these co-receptors were not required for this specific signaling pathway.
Why it matters
Understanding these fundamental cellular mechanisms provides deeper insight into tissue development and the origins of various diseases linked to Wnt signaling.
Nature Communications ( 2026 ) Cite this article
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