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Nature·2 min read·hard

The human microbiome and chronic disease: ten strategic priorities for research and public health

B
Blaser, Martin J.
The human microbiome and chronic disease: ten strategic priorities for research and public health
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An international group of scientists convened by the US Department of Health and Human Services has outlined ten strategic priorities for microbiome research. The initiative aims to leverage advancements in biomedical science to improve public health outcomes regarding chronic diseases.

Why it matters

This research framework sets the agenda for future medical breakthroughs in understanding how the human microbiome influences long-term health.

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Nature Medicine ( 2026 ) Cite this article

The human microbiome has emerged as one of the most consequential frontiers in biomedical science. An international group of leading microbiome scientists, convened by the US Department of Health and Human Services, presents a strategic vision for realizing its potential to transform public health.

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Subjects Diseases Medical research Microbiome Influences on Human Health and Disease References Gilbert, J. A. et al. Nat. Med. 31 , 1099–1113 https://doi.org/10.1038/s41591-025-03615-9 (2025).

Asnicar, F. et al. Nat. Med. 27 , 321–332 https://doi.org/10.1038/s41591-020-01183-8 (2021).

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