TechCrunch Disrupt 2026’s biggest stage features leaders from Amazon, Replit, Tether, with much more to come

TechCrunch announces the speaker lineup for its 2026 Disrupt conference in San Francisco. The event will focus on the practical application of AI in building, funding, and scaling startups.
Why it matters
As a major industry event, it signals the current shift from AI hype toward operational execution and infrastructure development.
The Disrupt Stage is where many of the biggest conversations in technology happen, with a legacy that stretches back for more than a decade. The names that have taken to the stage are so big, they are synonymous with the past era of startups and the new era of AI and major incumbents: Zuckerberg, Benioff, Musk, Kalanick, Mayer, Dorsey.
And at TechCrunch Disrupt 2026 , we’re tackling the biggest topic of the year with some of the biggest names to match. We’re homing in on what it actuallytakes to build, fund, and scale in the age of AI.
From October 13–15 in San Francisco at Moscone Center, founders, investors, and technologists will hear directly from the people shaping the future of software, infrastructure, finance, security, and computing.
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