Study Reveals Menopause Triggers Sudden Biological Changes Across Multiple Body Systems

Menopause involves abrupt physiological changes across multiple body systems, rather than being an entirely gradual process, according to a new study published in Nature Medicine.Researchers analysed more than 300 million laboratory tests from over one million women in the US and Israel between 1999 and 2024.In the US dataset, 52 of 90 laboratory tests showed statistically significant abrupt changes around menopause, including measures of bone health, liver and kidney function, and blood chemistry.Hormonal changes began much earlier, with anti-Müllerian hormone and follicle-stimulating hormone showing accelerated changes about 15 years before the final menstrual period.Researchers found that menopausal hormone therapy was associated with differences in 39 laboratory measurements, suggesting it may moderate some changes, although further research is needed..Analysis of more than 300 million laboratory tests suggests menopause involves sudden physiological changes across multiple organs, with early hormonal shifts beginning more than a decade before the final menstrual period.Menopause is not…