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Science Daily·4 min read·hard

Stanford scientists regrow lost cartilage and reverse arthritis in major breakthrough

Stanford scientists regrow lost cartilage and reverse arthritis in major breakthrough
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Stanford researchers have identified a protein, 15-PGDH, that contributes to cartilage degradation and aging. Blocking this protein has shown success in regrowing cartilage in mice and human tissue samples, offering a potential future treatment for osteoarthritis.

Why it matters

This breakthrough could revolutionize the treatment of osteoarthritis, potentially eliminating the need for invasive joint replacement surgeries for millions of people.

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A treatment that targets a protein linked to aging has restored lost knee cartilage in older mice and prevented arthritis from developing after serious joint injuries, according to a Stanford Medicine-led study.

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