Six-gene scoring system could help predict leukemia survival
Researchers at the Center for Genomic Regulation have identified a six-gene scoring system that predicts survival outcomes for patients with acute myeloid leukemia. This new method, called PHFScore, offers a more accurate prognosis than analyzing single genes alone.
Why it matters
This discovery could lead to more personalized treatment plans and improved prognostic testing for patients diagnosed with aggressive blood cancers.
edited by Sadie Harley , reviewed by Robert Egan
This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility:
Add to Preferred Sources Spleen tissue from a mouse without PHF19 (left) and a mouse with normal PHF19 function (right). Dense clusters of immune cells sit within blood-rich regions in pink. Without PHF19, cells are altered in their differentiation process. Credit: Gianni Gamarra/Centro de Regulación Genómica The activity of six different genes can help determine survival in patients with acute myeloid leukemia (AML), according to a study published in Science Advances . The findings by researchers at the Center for Genomic Regulation (CRG) in Barcelona lay the foundations for new ways of predicting how patients will fare with a type of blood cancer that has widely variable outcomes from one patient to the next.
Get smarter about the news
Sign up free for a feed built around what you actually care about, Dive Deeper research on any story, and the full text of every article.
Create free accountAlready have an account? Sign in