Silent, motion-resistant fMRI expands scans in behaving mice
A new fMRI technique called SORDINO allows for silent, motion-resistant brain scans in awake, behaving mice. This method overcomes the limitations of traditional anesthesia and high-noise scanning environments.
Why it matters
This technology enables more accurate and naturalistic brain imaging in animal models, potentially leading to better insights into neurological function.
A new functional MRI (fMRI) technique cuts down on scanning noise and motion-related artifacts, broadening the range of brain scans possible in awake and behaving animals, according to a new study .
“This is really groundbreaking work,” says Alessandro Gozzi , director of the Functional Neuroimaging Laboratory at the Istituto Italiano di Tecnologia, who was not involved in the study. One of the biggest challenges for scientists doing fMRI in awake animals has been conventional methods’ sensitivity to motion. The degree to which the new method reduces motion artifacts “is really remarkable,” Gozzi says. “The fact that it is silent is just a bonus to me.”
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