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The Hindu·4 min read·hard

Shilpa Medicare and Gate2brain Sign Strategic Equity Partnership to Advance First-in-Class Brain Cancer Therapy

Shilpa Medicare and Gate2brain Sign Strategic Equity Partnership to Advance First-in-Class Brain Cancer Therapy
AI Summary

Shilpa Medicare has entered a strategic equity partnership with Gate2Brain to develop a novel therapy for pediatric brain cancers. The collaboration focuses on using a proprietary peptide shuttle to improve drug delivery across the blood-brain barrier.

Why it matters

This partnership combines specialized biotechnology with manufacturing scale to address high-mortality pediatric oncology markets.

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Shilpa Biocare Pvt Ltd, a subsidiary of Shilpa Medicare Limited (BSE/NSE: SHILPAMED) has entered a strategic equity partnership with Gate2Brain, S.L., a biotechnology company focused on CNS therapeutics. Shilpa becomes a strategic shareholder and CMC, manufacturing, and regulatory partner for G2B-002 — Gate2Brain’s lead program targeting deadly pediatric brain cancers, DIPG and pGBM, both with Orphan Drug Designation from the US FDA and EMA. G2B-002 uses Gate2Brain’s proprietary MiniAp4 peptide shuttle to deliver SN-38 across the blood-brain barrier, demonstrating up to 100-fold greater brain drug transport preclinically. First-in-human trials are anticipated by FY28.

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The article is a straightforward business announcement regarding a corporate partnership and medical research.

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