Times of India·4 min read·hard

Sergey Brin’s Foundation backed study to detect Parkinson’s in early stages

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Sergey Brin’s Foundation backed study to detect Parkinson’s in early stages
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The Sergey Brin Family Foundation has supported research that led to a breakthrough in detecting Parkinson's disease using a biological test. The test, known as αSyn-SAA, identifies abnormal protein aggregates in cerebrospinal fluid, marking a significant advancement in early diagnosis.

Why it matters

This diagnostic tool could fundamentally change how neurodegenerative diseases are treated by allowing for early intervention before physical symptoms appear.

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The Sergey Brin Family Foundation, a private philanthropic organisation established in 2014 by Google co-founder Sergey Brin, supports a variety of important issues. These include research to understand, treat and improve the lives of people with central nervous system conditions and accelerating next-generation energy innovation. The foundation has also backed researchers who are running the Parkinson’s Progression Markers Initiative (PPMI) and achieved a major scientific milestone in 2023 by validating a biological test capable of spotting Parkinson’s pathology in living patients before physical symptoms surface.The diagnostic breakthrough, detailed in a study published in The Lancet Neurology, centers on an assay known as αSyn-SAA (alpha-synuclein seed amplification assay). By analysing cerebrospinal fluid, the test identifies abnormal protein aggregates, offering the first objective biological marker to confirm the disorder since British physician James Parkinson first described it in 1817.Building on these findings, The Michael J.

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