Scientists tested 39 sweeteners and found unexpected gut effects
A University of Cambridge study suggests that certain sweeteners, particularly when combined with specific medications, may negatively impact gut bacteria. Researchers emphasize that these findings are preliminary and based on laboratory experiments.
Why it matters
Understanding the interaction between common food additives and the human microbiome is critical for long-term public health and dietary guidelines.
Commonly used sweeteners can directly interfere with the growth of bacteria that help support a healthy gut, according to laboratory research from the University of Cambridge.
The strongest effect appeared when researchers combined isosteviol, a sweetener used by the food and beverage industry, with the antidepressant duloxetine. Together, the two compounds sharply reduced the growth of two important bacterial species associated with digestive health, blood sugar regulation, and immune function.
The scientists caution that the experiments were conducted in a laboratory rather than in people. More research will therefore be needed to determine whether the bacterial changes lead to meaningful health effects under real-world conditions.
Sweeteners May Not Be Biologically Inactive
Sweeteners are found in countless everyday products, including soft drinks, candy, desserts, breakfast cereals, snacks, and some medications. They are commonly promoted as alternatives that provide sweetness with less sugar or fewer calories.
Get smarter about the news
Sign up free for a feed built around what you actually care about, Dive Deeper research on any story, and the full text of every article.
Create free accountAlready have an account? Sign in