Scientists reveal how blood cells release key signaling lipid
Researchers from NUS Medicine and St. Jude Children's Research Hospital have identified how the protein MFSD2B transports the signaling lipid S1P out of blood cells. Using cryo-electron microscopy, the team mapped the protein's structure to understand how it facilitates the release of S1P into the bloodstream.
Why it matters
Understanding this transport mechanism provides critical insights into how blood vessels remain healthy and how immune cells function, potentially aiding future drug development.
edited by Gaby Clark , reviewed by Robert Egan
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Add as preferred source Credit: Pixabay/CC0 Public Domain Scientists from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), and St. Jude Children's Research Hospital in the United States have discovered how blood cells release an important signaling fat called sphingosine-1-phosphate, or S1P, into the bloodstream.
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