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Scientists reprogram brain immune cells to fight Alzheimer's: Study

Scientists reprogram brain immune cells to fight Alzheimer's: Study
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Researchers have identified a molecule called OLE that can reprogram brain immune cells to better protect against Alzheimer's disease. In animal models, this treatment reduced toxic beta-amyloid plaques and improved memory performance.

Why it matters

This discovery offers a potential new therapeutic pathway for treating Alzheimer's, a condition that currently lacks effective disease-modifying treatments.

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Representative Image (Photo/Reuters). Image Credit: ANI SHARE A newly discovered molecule, OLE, restored the brain's immune cells to a more protective state in Alzheimer's disease models. The treatment reduced the accumulation of toxic plaques and improved memory performance, highlighting its potential as a promising new therapeutic strategy. Researchers in Spain and Switzerland have identified an experimental molecule that may help restore the brain's natural defences against Alzheimer's disease. The compound, known as OLE, appears to "reprogram" microglia, the brain's immune cells, allowing them to regain some of their protective abilities.

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