Scientists map how the flu virus rewires the human cell from the inside
Researchers at EMBL Hamburg have mapped the protein-protein interactions between the influenza A virus and human cells at a structural level. This detailed visualization aims to assist in the development of more effective vaccines and drug therapies.
Why it matters
Understanding the molecular mechanics of how viruses hijack host cells is critical for creating next-generation antiviral treatments.
edited by Gaby Clark , reviewed by Andrew Zinin
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Add as preferred source Researchers studied the extensive network of protein-protein interactions that forms in cells infected with the influenza A virus. Credit: Daniela Velasco/EMBL Researchers at EMBL Hamburg and collaborators at the Leibniz Research Institute for Molecular Pharmacology (FMP) have mapped how the influenza A virus rewires infected human cells in unprecedented detail. To do this, the researchers used a customized experimental workflow to directly observe how proteins interact inside intact infected cells.
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