Scientists discover neurons must break their DNA to build the brain
Researchers have discovered that developing neurons in the brain intentionally break their own DNA to navigate through tight tissue spaces during brain formation. This damage is a normal part of development and is efficiently repaired by the cell.
Why it matters
This discovery provides new insights into brain development and may help scientists better understand the origins of various neurological conditions linked to DNA repair failures.
As the brain develops, newly formed neurons must travel through tightly packed tissue to reach their final destinations in the cerebral cortex, where they become part of the brain's communication network. This journey forces the cells through narrow gaps between fibers and neighboring cells.
The article reports on peer-reviewed scientific research in a neutral, informative manner.
Get smarter about the news
Sign up free for a feed built around what you actually care about, Dive Deeper research on any story, and the full text of every article.
Create free accountAlready have an account? Sign in