Scientists discover how the brain adds new information to old memories

Researchers have identified a neurological mechanism in the hippocampus that helps the brain distinguish between new information and old memories. The study suggests that a specific type of neuron uses inhibition to dynamically manage how memories are stored and retrieved.
Why it matters
Understanding how the brain processes and separates memories could lead to breakthroughs in treating memory-related disorders and cognitive decline.
Imagine, for example, a building site in your neighbourhood. The human brain can remember three key stages of it: the original state before the renovation, the construction work itself, and the final outcome once the project is completed. But how does it manage not to muddle those three memories?The Institute of Neurosciences, a public research centre made up of CSIC and Miguel Hernández University, believes it has found this neurological mechanism in its new study published in the journal 'PLOS Biology' (source in Spanish).The team at its Neuronal Network Plasticity laboratory thinks the brain uses a region of the hippocampus known as the dentate gyrus, which is dedicated to forming new memories. There, a specific type of neuron inhibits the activity of other cells to help integrate new experiences.To test this idea, the researchers studied this inhibition process in mice, increasing or reducing it.
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