Scientists Develop First Comprehensive Atlas of Human Cellular Senescence in Aging
The NIH's Cellular Senescence Network (SenNet) has released its first comprehensive atlas mapping how aging affects human cells. Researchers from Yale and other institutions identified how 'zombie cells' contribute to inflammation and chronic diseases like cancer and Alzheimer's.
Why it matters
This research provides a foundational map for understanding the biological mechanisms of aging, potentially leading to new medical interventions.
A massive scientific initiative to decode how aging reshapes the human body reached a major milestone this month. The National Institutes of Health (NIH) Cellular Senescence Network (SenNet) published its first wave of discoveries, highlighted by a cover commentary in the journal Cell led by Rong Fan, PhD, Harold Hodgkinson Professor of Biomedical Engineering at Yale School of Engineering and Applied Science (SEAS) and of Pathology at Yale School of Medicine (YSM), alongside researchers from nine other institutions.
The article is a scientific summary of peer-reviewed research findings.
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