Nature·3 min read·hard

Role of lactylation-related genes in heatstroke-induced ventricular arrhythmias by integrated transcriptomic and proteomic analysis and experimental validation

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Xu, Liao
Role of lactylation-related genes in heatstroke-induced ventricular arrhythmias by integrated transcriptomic and proteomic analysis and experimental validation
AI Summary

This study investigates the molecular mechanisms linking heatstroke to cardiac injury and ventricular arrhythmias in rats. Researchers found that increased protein lactylation and specific gene expression changes are associated with heart complications during heatstroke.

Why it matters

Understanding the biological pathways of heatstroke-induced cardiac damage could lead to better clinical interventions for heat-related illnesses.

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Scientific Reports ( 2026 ) Cite this article

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply.

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