Ribosome-based gene circuit lets cells read six signals and trigger responses
Researchers at POSTECH have developed a ribosome-based gene circuit platform called RATEX that allows cells to process multiple molecular signals simultaneously. This technology enables cells to function like living computers by autonomously making decisions and triggering programmed responses.
Why it matters
This advancement in synthetic biology could revolutionize medical treatments and cellular engineering by allowing for more complex, logic-based biological interventions.
by Pohang University of Science and Technology
edited by Gaby Clark , reviewed by Andrew Zinin
This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility:
Add as preferred source Signal processing capabilities of the RATEX platform and schematic of cellular programming using gene circuits designed on this platform. Credit: POSTECH The molecular machinery that normally builds proteins inside cells has now taken on a new role as a "switch." A research team at POSTECH (Pohang University of Science and Technology) has developed a new 'RNA-based smart gene circuit' platform that can simultaneously read multiple signals inside a cell, make its own decisions and autonomously generate programmed responses. This represents a step beyond simple genetic manipulation toward an era in which cells themselves function as "living computers."
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