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Walter and Eliza Hall Institute of Medical Research·2 min read·hard

Researchers uncover hidden defects in immune cells linked to coeliac disease

Researchers uncover hidden defects in immune cells linked to coeliac disease
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Researchers at the Walter and Eliza Hall Institute have identified specific defects in CD4 helper T cells that may contribute to coeliac disease. The study uses a new assay to measure how these immune cells maintain activation signals.

Why it matters

Understanding the cellular mechanisms of autoimmune diseases like coeliac disease is crucial for developing targeted therapies and diagnostic tools.

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The new study was led by Dr Vanessa Bryant , Professor Phil Hodgkin and Dr Susanne Heinzel with clinical expertise from Snow Centre Director, Professor Jason Tye-Din .

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