nature.com·4 min read·hard

Recovery of genomic and transcriptomic profiles from decades-old FFPE brain tissues

C
Christiansen, Caroline Robinson
Recovery of genomic and transcriptomic profiles from decades-old FFPE brain tissues
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Researchers have successfully extracted and sequenced DNA and RNA from decades-old FFPE brain tissue from the Danish Brain Collection. The study demonstrates that improved extraction techniques can yield biologically informative data from degraded samples.

Why it matters

This breakthrough unlocks a massive archive of historical brain tissue, potentially advancing research into neurodegenerative and psychiatric disorders.

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Scientific Reports ( 2026 ) Cite this article

We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply.

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