Real-world study of Oregon's nonmedical psilocybin program shows promise

A new study of Oregon's state-regulated psilocybin program indicates that most participants found the experience beneficial and safe. The findings suggest a viable alternative pathway for psychedelic use outside of traditional medical clinical trials.
Why it matters
As states move toward legalization, this data provides critical real-world evidence on the safety and efficacy of non-medical, supervised psychedelic use.
JDawnInk/Getty Images New research on the experience of people who took magic mushrooms through Oregon's homegrown psychedelic industry – the first program of its kind in the U.S. – is offering a largely favorable picture.
Health A dose of psilocybin helps smokers quit in new study The study – based on almost 350 people who took the drug at state-licensed centers – is the largest yet to look at the real-world implications of offering regulated psilocybin, the active ingredient in magic mushrooms.
Most of the participants described their trip as beneficial and more than half ranked it among the most meaningful experiences of their life. Meanwhile, the data suggest the program was overall quite safe.
Only a very small number had "serious adverse reactions," according to the analysis published on Wednesday in the medical journal JAMA Network Open .
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