Newswise·3 min read·hard
Premature blood stem cell aging in sickle cell disease may be reversible
✦AI Summary
A study from St. Jude Children's Research Hospital suggests that premature aging of blood stem cells in sickle cell disease patients may be reversible using senolytic drugs. These drugs target aging-related processes to restore the bone marrow's ability to produce healthy blood cells.
(L to R) First author Aditya Barve, PhD, St. Jude Department of Hematology, co-corresponding author Akshay Sharma, MBBS, MSc, St. Jude Department of Bone Marrow Transplantation & Cellular Therapy, and senior co-corresponding author Shannon McKinney-Freeman, PhD, St. Jude Department of Hematology.
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