Precision targeting cancer
Researchers in India have developed light-driven nanobots capable of targeting and destroying breast cancer cells using near-infrared light. Additionally, a separate team has created a low-cost portable device for detecting water contaminants.
Why it matters
These innovations represent significant advancements in precision medicine and accessible environmental monitoring technology.
Researchers at the Institute of Nano Science and Technology (INST), Mohali, have developed light-driven multifunctional nanobots that can target and destroy breast cancer cells, potentially offering a new approach to precision cancer therapy.
The team, led by Dr Jiban Jyoti Panda of INST, in collaboration with Dr Santosh K Gupta of BARC, designed up-conversion nanoparticle-based nanobots that convert near infrared (NIR) light into heat and move towards the light source.
The nanobots are coated with a photosensitiser that generates cancer-killing reactive oxygen species under NIR light, while a folic acid coating enables them to selectively target breast cancer cells overexpressing folate receptors. The combined photothermal and photodynamic effects enhance tumour destruction. Unlike light-powered nanorobots that rely on ultraviolet or visible light with limited tissue penetration, the new system uses NIR light, which penetrates deeper and is less damaging to healthy cells.
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