Potential protective effects of metformin on remote organ injury in the liver, kidney, and lung following experimental lower-extremity ischemia–reperfusion in non-diabetic rats
A study on Wistar albino rats indicates that metformin may help reduce oxidative stress and organ damage following lower-extremity ischemia-reperfusion injury. The findings suggest that the drug provides protective effects for the liver, kidney, and lung in non-diabetic subjects.
Why it matters
This research explores potential new therapeutic applications for a widely used diabetes medication in emergency trauma scenarios.
Scientific Reports ( 2026 ) Cite this article
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