Phosphoprotein-enriched proteomics identifies heat shock cognate 71 protein as a host factor supporting chikungunya virus replication in macrophages
Researchers identified the heat shock cognate 71 protein (HSC71) as a critical host factor that supports the replication of the Chikungunya virus in macrophages. Inhibiting this protein reduced viral replication, offering a potential target for future antiviral therapies.
Why it matters
Provides a potential pathway for developing new treatments for Chikungunya, a virus that causes significant inflammatory illness.
Scientific Reports ( 2026 ) Cite this article
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