Ophthalmology Advisor·4 min read·hard

Pediatric Patients Face Higher Postop Endophthalmitis Risk

Pediatric Patients Face Higher Postop Endophthalmitis Risk
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A large-scale study using the IRIS Registry indicates that pediatric patients face a higher risk of postoperative endophthalmitis compared to adults. The research highlights that open globe repair surgery carries the highest infection risk across all age groups.

Why it matters

Identifying higher-risk patient demographics allows surgeons to adjust prophylactic measures and postoperative care to improve patient safety.

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Open globe repair surgery carries the highest 1-month postoperative rate of endophthalmitis, according to research published in Ophthalmology .

Investigators reviewed 2016 to 2024 data from the American Academy of Ophthalmology Intelligent Research in Sight (IRIS (r) ) Registry to produce a large-scale assessment of first-time endophthalmitis incidence in 9,615,960 adult and pediatric patients (16,318,009 eyes) within 30 days of ophthalmic procedures.

The investigators identified 17,457,881 procedures (85% cataract surgery; 5.85% combined cataract and glaucoma; 1.8% scleral buckle) and found that, overall, endophthalmitis was most common in open globe repair (1 per 107), followed by penetrating keratoplasty (1 per 250) and trabeculectomy (1 per 1000).

In adults, endophthalmitis rates were highest in open globe repair (1 per 106), penetrating keratoplasty (1 per 243), and combined cataract and vitrectomy surgery (1 per 374).

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