Ozempic and Wegovy may raise hair loss risk in some men

A study from NYU Langone Health suggests that men with a genetic predisposition to hair loss may face an increased risk of shedding when using GLP-1 receptor agonist drugs like Ozempic and Wegovy. Researchers believe these medications may interact with the GLP1R gene, which is linked to androgenetic alopecia.
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As the popularity of weight-loss drugs grows, understanding potential side effects is crucial for patients and doctors managing long-term treatment plans.
Men who are already genetically predisposed to the most common type of hair loss may face an additional 7 percent risk of losing hair when using drugs such as Ozempic, Wegovy, and Zepbound for type 2 diabetes and obesity, according to a new study.
Researchers at NYU Langone Health examined the GLP1R gene, which naturally influences levels of glucagon-like peptide-1 (GLP-1) receptor proteins in the body. They used activity involving this gene as an indicator of GLP-1 agonist activity. Greater GLP1R activity is associated with higher levels of GLP-1 receptor proteins.
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