Olive Oil Before Carbs Blunts Blood Sugar Spike in Mice
Researchers at Kyoto University found that consuming olive oil before carbohydrates can help blunt blood sugar spikes in mice. The study suggests that meal-sequencing could be a sustainable dietary strategy for managing glucose levels in diabetic patients.
Why it matters
This research offers a potential non-pharmacological approach to diabetes management by focusing on the order of food consumption rather than restrictive dieting.
Activity Database on Education and Research
Kyoto, Japan -- In treating diabetes, post-meal elevation of glucose levels is an important therapeutic target. Existing clinical studies indicate that eating vegetables, protein, or fat before carbohydrates can moderate a post-meal rise in blood glucose, pointing to the potential of meal-sequencing as a simple and sustainable dietary strategy.
Scientists have often attributed the benefits of this strategy to slower gastric emptying and greater secretion of incretin hormones, such as GLP-1, that decrease blood glucose levels. However, the roles that gut and pancreatic hormones, as well as neural pathways, play in this process have remained less understood. This motivated an international team of researchers to investigate how the timing of fat intake influences glucose levels, hormone secretion, and gastric emptying.
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