NHS Cancer Blood Test Trial Publishes First Papers
A large-scale NHS trial involving 142,000 volunteers evaluated the effectiveness of the Galleri blood test in detecting early-stage cancers. While the test showed promise in identifying cancer signals, the study did not meet its primary goal of reducing the number of late-stage cancer diagnoses.
Why it matters
The results provide critical data on the viability of multi-cancer early detection blood tests in public health screening programs.
A large-scale cancer trial investigating whether a blood test can help the NHS detect cancer early has published its first papers, both in leading international journals.
University of Exeter is part of the team assessing the NHS-Galleri trial , which involved 142,000 volunteers aged 50-77 from eight regions of England.
The trial is studying whether the Galleri (r) multi-cancer early detection test alongside existing cancer screening can help to find cancer early. The blood test can detect a 'signal' shared by many different types of cancer in a sample of a person's blood.
Professor Richard Neal , at the University of Exeter Medical School , is trial co-lead, and author on the two papers to detail the first results from the trial, including whether using the Galleri (r) multi-cancer early detection (MCED) blood test changed the stage at which cancers were diagnosed and how the test performed.
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