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ScienceDaily·4 min read·hard

New vitamin B12 therapy shows promise against deadly brain cancer

New vitamin B12 therapy shows promise against deadly brain cancer
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Researchers have developed a modified vitamin B12 compound, nitrosylcobalamin, that can cross the blood-brain barrier to target glioblastoma tumors. Early studies in animal models show promise for this treatment as a potential therapy for aggressive brain cancer.

Why it matters

Glioblastoma is a highly lethal and treatment-resistant cancer; finding ways to bypass the blood-brain barrier is a critical breakthrough in oncology.

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A newly published study in Oncoscience explores a potential new approach to treating glioblastoma, an aggressive form of brain cancer that remains extremely difficult to treat. The paper is titled "Selective blood-brain barrier penetration and tumor targeting of nitrosylcobalamin in glioblastoma: Pharmacokinetics, tissue distribution, and synergistic activity with trail and temozolomide."

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