New Type Of Human Jumping Gene Found In Poxvirus
Scientists have discovered a unique human gene, BC200, within a poxvirus that functions as both a brain-related gene and a 'jumping gene' capable of moving within genomes. This dual functionality challenges previous understandings of how transposable elements evolve to serve cellular purposes.
Why it matters
This discovery provides new insights into evolutionary biology and the complex mechanisms that govern human genetic function and disease.
Scientists found a human genetic element in a poxvirus and discovered it was both an important gene for brain function and a jumping gene capable of moving and inserting itself in genomes.
A study published Sept. 24 in Science reports that the gene, called BC200, combines a mix of characteristics that have never been seen before.
BC200 is mostly expressed in neurons but originated millions of years ago from a transposon or 'jumping gene', a non-coding genetic element known for its ability to move and insert itself in genomes.
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