New research may predict when Alzheimer’s symptoms begin

LOUISVILLE, Ky. (WAVE) - Scientists may be getting closer to predicting when a person at high risk for Alzheimer’s disease could begin showing symptoms.

A new study at Columbia University found combining a blood test with genetic testing may help doctors estimate when cognitive decline could begin.

Researchers focused on a blood marker called P-TAU 217, and a genetic variant known as APOE4, both linked to a higher risk of Alzheimer’s disease.

The study found people with elevated levels of TAU and at least one copy of the APOE4 variant were more likely to develop cognitive impairment.

Some showed signs of decline within three to four years.

Dr. Greg Cooper of Norton Neuroscience Institute said the findings could help identify patients on a path towards Alzheimer’s before major symptoms appear.