Multiple brain regions use same recipe for neural wiring
Neuroscientists have discovered that the human brain reuses specific adhesion molecules, TEN3 and LPHN2, to guide neural wiring across different regions. This mechanism explains how complex neural circuits form despite a limited number of molecular cues.
Why it matters
Understanding the fundamental wiring of the brain provides insights into neurodevelopmental conditions like autism.
The human brain forms trillions of synapses using only a few thousand cell-surface proteins to guide the process. How can distinct functional circuits form when there are far more neurons than molecules to guide them?
Scientific reporting based on peer-reviewed research.
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