Molecular electromagnetic sensor may enable remote-controlled gene therapy
Researchers at Dongguk University have developed a gene switch that can be controlled remotely using electromagnetic fields. This noninvasive technology aims to provide more precise control over gene expression for therapeutic applications compared to existing drug or light-based methods.
Why it matters
This innovation could lead to safer and more effective gene therapies for genetic disorders by allowing doctors to modulate gene activity without invasive procedures.
edited by Sadie Harley , reviewed by Robert Egan
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Add as preferred source Graphical abstract. Credit: Cell (2026). DOI: 10.1016/j.cell.2026.03.029 The deoxyribonucleic acid (DNA) of living organisms contains regulatory elements that control when, where and to what extent specific genes are turned on or off. They can be co-opted to create "gene switches" that hold significant potential for understanding gene expression and for therapeutic applications, particularly for the noninvasive treatment or management of genetic disorders.
In recent years, researchers have developed several gene switches that enable the remote control of gene expression in living organisms using stimuli such as drugs, light, heat, ultrasound and electrical signals.
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