Menopause is marked by a body-wide physiological 'cliff,' study suggests

A large-scale study published in Nature Medicine suggests that menopause is preceded by abrupt physiological changes across multiple body systems, occurring as early as a decade before the final menstrual period. Researchers used a computational method to analyze millions of lab tests to identify these 'cliff-like' biological shifts.
Why it matters
Understanding these early physiological markers could improve the detection and management of health changes associated with the transition to menopause.
edited by Lisa Lock , reviewed by Robert Egan
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Add to Preferred Sources Credit: Unsplash/CC0 Public Domain The final menstrual period is preceded by abrupt "cliff-like" biological changes across multiple body systems, some of which show early signs more than a decade beforehand, according to research published in Nature Medicine . The findings suggest that menopause-related physiological changes may occur over a shorter time frame than previously thought and advance our understanding of how early these changes can be detected.
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