The Straits Times·3 min read·medium

magnetic pulses reprogramme immune cells to fight breast cancer

J
Judith Tan
magnetic pulses reprogramme immune cells to fight breast cancer
AI Summary

Researchers at the National University of Singapore have developed a method using low-intensity magnetic pulses to reprogram immune cells to fight breast cancer. This approach successfully eradicated tumors in preclinical models without the side effects associated with chemotherapy.

Why it matters

This breakthrough offers a potential non-invasive alternative to chemotherapy, which could significantly improve patient outcomes and quality of life in cancer treatment.

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(From left) National University of Singapore researchers Viresh Krishnan Sukumar, Alex Tai and Alfredo Franco-Obregon have successfully used this approach for targeted breast cancer therapy without the use of chemotherapy.

Listen Summarise Researchers at the National University of Singapore use low-intensity magnetic pulses (PEMFs) to reprogramme immune cells and attack breast cancer without chemotherapy. PEMFs eradicated tumours in 75% of preclinical models by inducing calcium overload and metabolic stress in cancer cells while sparing healthy tissue. Phase I safety trials are complete; Phase II will test effectiveness in patients, aiming to reduce chemotherapy dosage and side effects while improving outcomes. AI generated

SINGAPORE – Researchers from the National University of Singapore (NUS) have found that using intermittent, low-intensity magnetic pulses could transform a corrupted class of immune cells that typically promote cancer growth into cells that attack and destroy cancer cells.

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