Lower cardiac output predicts faster brain loss in carriers of Alzheimer's disease risk gene
A longitudinal study from Vanderbilt Health indicates that lower cardiac output is linked to faster brain atrophy in older adults carrying the APOE-e4 Alzheimer's risk gene. The findings suggest that cardiovascular health plays a critical role in neurodegeneration.
Why it matters
Understanding the link between heart health and brain aging could lead to new preventative strategies for Alzheimer's disease.
edited by Gaby Clark , reviewed by Andrew Zinin
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Add as preferred source Credit: Gustavo Fring from Pexels In a longitudinal study conducted at Vanderbilt Health, including investigators from the Vanderbilt Memory and Alzheimer's Center (VMAC), researchers found that lower cardiac output is associated with accelerated cerebral atrophy among older adults who carry the APOE-e4 allele, a genetic risk factor for Alzheimer's disease.
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