Long-Term Study Finds HRT Not Linked to Heart Disease Risk
A large-scale study of over 52,000 women in Israel found no link between contemporary hormone replacement therapy (HRT) and increased risks of heart disease or stroke. These findings support recent FDA decisions to remove 'black box' warnings from HRT products.
Why it matters
This research could significantly change clinical practice and improve quality of life for menopausal women who previously avoided HRT due to outdated cardiovascular safety concerns.
Embargoed until 4 a.m. CT/5 a.m. ET, Monday, Nov. 2, 2026
DALLAS, Nov. 2, 2026 - Contemporary hormone replacement therapy (HRT) was not associated with an increased risk for heart attack, stroke, blood clots or death among women ages 45 to 59, according to a large, long-term study of over 52,000 women in Israel. The findings from this new, independent, preliminary research will be presented at the American Heart Association's Scientific Sessions 2026. The meeting, Nov. 6-9, in Chicago, is a premier global exchange of the latest scientific advancements, research and evidence-based clinical practice updates in cardiovascular science.
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