Localized enteric neural deficiency and reduced nerve-mediated anorectal contractility in immunodeficient RetS812F/+ mice
Researchers have developed a new immunodeficient mouse strain, B6RGS-Ret S812F/+, to study enteric nerve deficiencies. This model provides a necessary environment for testing human cell-based therapies for the enteric nervous system.
Why it matters
This advancement facilitates preclinical research into treatments for gastrointestinal nerve disorders, potentially accelerating the development of regenerative medicine.
Scientific Reports ( 2026 ) Cite this article
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